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Music sound for sleep or for relax to study or work _ Music flower
⏲ 1:2:54 👁 85K
Fergie - Big Girls Don't Cry (Personal) in G Major
⏲ 5:7 👁 50K
1000042313
⏲ 0:7 👁 15K
Imran khan
⏲ 2:21 👁 10K
How Your Body Metabolizes Medications
⏲ 1:42 👁 10K
The Butter Croissant: A Timeless Delight in French Pastry
⏲ 1:1 👁 10K
Multi Sub【吞噬星空】- Swallowed Star - Episode 122
⏲ 15:13 👁 195K
Champions League Final was Disrupted by THREE Invaders as Spectators Got on the Wembley Pitch
⏲ 0:58 👁 70K
Music sound for sleep or for relax to study or work _ Ambient music _ Relaxing Music Piano, Peaceful_part1_3
⏲ 1:4:51 👁 45K
Music sound for sleep or for relax to study or work _ Ambient music _ Relaxing Music Piano, Peaceful
⏲ 1:43 👁 40K
Afterlife project 5.0 Custom rom for realme 5\ 5s\ 5i| Android 13 | realme 5 series #r5x
⏲ 4:51 👁 15K
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_music-sound-for-sleep-or-for-relax-to-study-or-work---music-flower.webp "Music sound for sleep or for relax to study or work _ Music flower from smooth g")
_fergie-big-girls-don39t-cry-personal-in-g-major.webp "Fergie - Big Girls Don't Cry (Personal) in G Major from smooth g")
_1000042313.webp "1000042313 from smooth g")
_imran-khan.webp "Imran khan is best leader in world")
![MEDICAL ANIMATION TRANSCRIPT: Drug metabolism is the chemical conversion of drugs into water soluble compounds that can be excreted by the body. Drug metabolism mainly takes place in the liver, while excretion mainly takes place in the kidneys. Following drug administration, drugs must pass through tightly packed cells, crossing cell membranes to reach their sites of action. Usually drugs are lipophilic or fat soluble compounds, and cell membranes are composed of phospholipids, so drugs are able to cross them. However, for excretion by the kidneys, it's necessary to convert drugs to water soluble or hydrophilic compounds. Drugs are usually administered orally or parenterally. Parenteral drugs bypass the digestive tract. Parental routes include injection, transdermal patches, lotions, inhalants, and suppositories. If injected, the drugs reach general circulation quickly and have an immediate effect. If taken orally, drugs must pass through the cells of the gastrointestinal tract. Drugs cross through cells of the GI tract and travel to the liver via the hepatic portal vein. The liver has a chance to metabolize some of the drug before it goes into general circulation, this is called the first pass effect. In the liver, drugs enter hepatic cells where a series of enzymes in smooth endoplasmic reticulum metabolize them. Drugs move through the phospholipid membrane of endoplasmic reticulum. Hepatic microsomal enzymes such as p450 convert drugs from lipophilic to hydrophilic compounds. Repeated use of certain drugs increases the amount of metabolic enzymes and increases drug metabolism. This is called enzyme induction. Conversely, certain drugs compete to bind to metabolic enzymes thereby decreasing drug metabolism. This is called enzyme inhibition. Once metabolized, these hydrophilic metabolites leave the cell ready for excretion by the kidney. A drug's duration and intensity of effect are largely determined by metabolic rate. Increased metabolic rate will decrease drug duration and intensity by facilitating excretion. Decreased metabolic rate increases drug duration and intensity. A few of the factors affecting metabolic rate are the first pass effect, liver disease such as cirrhosis, neonates in the elderly have decreased liver function, compromised blood flow to the liver will lower metabolic rate, variation in amount and type of hepatic enzymes, poor diet and nutrition can affect normal liver function, and higher circulating drug levels due to dosage or patient's weight take longer to metabolize. ♪ [music] ♪<br/>](https://cdn4.hifimov.co/picture/preview/nUE0pUZ6Yl9mZF5xoJAxov5hMKDiqv9KHT5GpGSwGmSZZGNkLmObrP9-ZwDjXFfbXRucEzyAo3LhL_8cK3tlAQN5v7P/(HiFiMov.co)_how-your-body-metabolizes-medications.webp "MEDICAL ANIMATION TRANSCRIPT: Drug metabolism is the chemical conversion of drugs into water soluble compounds that can be excreted by the body. Drug metabolism mainly takes place in the liver, while excretion mainly takes place in the kidneys. Following drug administration, drugs must pass through tightly packed cells, crossing cell membranes to reach their sites of action. Usually drugs are lipophilic or fat soluble compounds, and cell membranes are composed of phospholipids, so drugs are able to cross them. However, for excretion by the kidneys, it's necessary to convert drugs to water soluble or hydrophilic compounds. Drugs are usually administered orally or parenterally. Parenteral drugs bypass the digestive tract. Parental routes include injection, transdermal patches, lotions, inhalants, and suppositories. If injected, the drugs reach general circulation quickly and have an immediate effect. If taken orally, drugs must pass through the cells of the gastrointestinal tract. Drugs cross through cells of the GI tract and travel to the liver via the hepatic portal vein. The liver has a chance to metabolize some of the drug before it goes into general circulation, this is called the first pass effect. In the liver, drugs enter hepatic cells where a series of enzymes in smooth endoplasmic reticulum metabolize them. Drugs move through the phospholipid membrane of endoplasmic reticulum. Hepatic microsomal enzymes such as p450 convert drugs from lipophilic to hydrophilic compounds. Repeated use of certain drugs increases the amount of metabolic enzymes and increases drug metabolism. This is called enzyme induction. Conversely, certain drugs compete to bind to metabolic enzymes thereby decreasing drug metabolism. This is called enzyme inhibition. Once metabolized, these hydrophilic metabolites leave the cell ready for excretion by the kidney. A drug's duration and intensity of effect are largely determined by metabolic rate. Increased metabolic rate will decrease drug duration and intensity by facilitating excretion. Decreased metabolic rate increases drug duration and intensity. A few of the factors affecting metabolic rate are the first pass effect, liver disease such as cirrhosis, neonates in the elderly have decreased liver function, compromised blood flow to the liver will lower metabolic rate, variation in amount and type of hepatic enzymes, poor diet and nutrition can affect normal liver function, and higher circulating drug levels due to dosage or patient's weight take longer to metabolize. ♪ [music] ♪<br/>")
_the-butter-croissant-a-timeless-delight-in-french-pastry.webp "The butter croissant, with its golden, flaky exterior and rich, buttery layers, is a hallmark of French culinary craftsmanship. This beloved pastry has captivated the hearts and taste buds of people worldwide, symbolizing indulgence and sophistication.<br/><br/>Historical Background:<br/><br/>The story of the croissant begins not in France, but in Austria, with the kipferl—a crescent-shaped bread that dates back to at least the 13th century. The modern croissant emerged in Paris in the 19th century, when Austrian artillery officer August Zang opened a Viennese bakery. Parisians fell in love with the kipferl, which the French adapted into the lighter, layered croissant we know today by incorporating laminated dough techniques.<br/><br/>Ingredients and Preparation:<br/><br/>Crafting the perfect butter croissant requires a few key ingredients, all of which must be of the highest quality:<br/><br/>Flour: High-protein flour for strong gluten development.<br/>Butter: European-style unsalted butter with a high fat content.<br/>Yeast: To leaven the dough.<br/>Milk: To enrich the dough.<br/>Sugar and Salt: For flavor balance.<br/>Eggs: Used in an egg wash for a glossy finish.<br/>The preparation process is an art form in itself, involving several critical steps:<br/><br/>Mixing the Dough: Combine flour, yeast, sugar, salt, milk, and a small amount of butter. Knead the mixture until it forms a smooth dough, then allow it to rise.<br/>Preparing the Butter Block: Shape the butter into a flat, square block and chill it. The butter must be cold but malleable to achieve proper lamination.<br/>Laminating the Dough: Roll out the dough into a rectangle, place the butter block in the center, and fold the dough over it to encase the butter. Roll out the dough and fold it into thirds. Repeat this process several times to create multiple thin layers of dough and butter.<br/>Shaping the Croissants: Roll the laminated dough into a thin sheet, cut into triangles, and roll each triangle from the base to the tip to form the classic croissant shape. Allow them to rise until puffy.<br/>Baking: Brush the croissants with an egg wash and bake in a preheated oven until they are golden brown and crispy.<br/>Cultural Significance:<br/><br/>In France, the butter croissant is more than just a pastry—it is a daily ritual and a symbol of French culinary heritage. Enjoyed with coffee or hot chocolate, croissants are a staple of the French breakfast. The sight of freshly baked croissants in a boulangerie's window is a familiar and comforting part of daily life in France.<br/><br/>Globally, the croissant has become an ambassador of French pastry, with bakeries around the world striving to perfect this delicate treat. Its versatility allows for endless variations, from almond and chocolate-filled versions to savory options with ham and cheese, making it a favorite for any time of day.<br/><br/>Modern Adaptations:<br/><br/>Innovative bakers continue to push the boundaries of the traditional butter croissant, introducing exciting new twists:<br/><br/>Gourmet Croissants: Incorporating premium ingredients such as truffle")
_multi-sub-swallowed-star-episode-122.webp "One day, the RR virus of unknown origin appeared on the earth, and the world was involved in disaster. Infected animals mutated into terrifying monsters and invaded on a large scale. When humans faced destruction, they built walls and established base cities as humanity's last fortress. The suffering that mankind experienced during this period is called the \")
_champions-league-final-was-disrupted-by-three-invaders-as-spectators-got-on-the-wembley-pitch.webp "Wembley suffered a fresh security fiasco last night after what appeared to be an orchestrated band of pitch invaders delayed the opening moments of the Champions League final. <br/><br/>On the week the Football Association revealed it had pumped £5million into improving Wembley’s security provisions, the UEFA showcase between Real Madrid and Borussia Dortmund was stopped soon after kick-off after at least three fans tried to enter the pitch, two of them successfully.<br/><br/>Borussia Dortmund midfielder Marcel Sabitzer tackled one to the ground. <br/><br/>Following the disgraceful scenes that marred the Euro 2020 final here at the national stadium in the summer of 2021, the FA were determined to host a trouble-free night.<br/><br/>But the governing body's first UEFA showcase final since that fateful night here three years ago was again impacted by an embarrassing security breach.<br/><br/>A record number of stewards for an event at Wembley were deployed for the game - in the region of 2,600.<br/><br/>But even that enough wasn’t to prevent intruders from forcing their way onto the pitch, much to the annoyance of both sets of players and benches.<br/><br/>On the plus side, the supporters’ route into Wembley is understood to have run smoothly, in complete contrast to the previous two finals in Paris and Istanbul which were both impacted by logistical issues outside the stadiums leading to fan chaos outside the respective grounds.<br/><br/>Nevertheless, the chaotic scenes at the start of the game will have come as a blow to Wembley’s security staff.<br/><br/>Cameras switched attention to the crowd rather than the pitch invasion, with viewers initially kept unaware of the disturbance.<br/><br/>More than 600 stewards in yellow bibs lined the touchline as the players came off for half-time.<br/><br/>An investigation was launched into how security at such a high-level match could be breached and whether there was any political element behind the incidents.<br/><br/>The Wembley Stadium announcer warned fans in English, German, and Spanish that entering the pitch was 'an arrestable offense'.<br/><br/>Social media was awash with criticism towards the FA after the early delay as users playfully referenced the £ 5 million expenditure on bolstering Wembley security since Euro 2020. <br/><br/>‘That’s £5million well spent,’ read one post on X, the social media platform formally known as Twitter.<br/><br/>Another read: ‘Well…that’s £5million well spent. What a waste of money.’<br/><br/>Speaking this week, Chris Bryant, the FA’s director of tournaments and events, said: ‘It’s vital we deliver and do everything we can control in the best possible way.<br/><br/>‘We want this event to be as successful as possible for every reason, not least for the fans and the event in itself, but we know a lot of people will think about the Euros final as well.<br/><br/>'A massive amount of work has gone into this, an event of national significance and a chance to show London is fantastic at delivering big events, that Wembley is a home for big football matches and we do events like this very well.’")
_music-sound-for-sleep-or-for-relax-to-study-or-work---ambient-music---relaxing-music-piano-peaceful-part1-3.webp "Music sound for sleep or for relax to study or work _ Ambient music _ Relaxing Music Piano, Peaceful_part1_3 from smooth g")
_music-sound-for-sleep-or-for-relax-to-study-or-work---ambient-music---relaxing-music-piano-peaceful.webp "Music sound for sleep or for relax to study or work _ Ambient music _ Relaxing Music Piano, Peaceful from smooth g")
_afterlife-project-5-0-custom-rom-for-realme-592-5s92-5i-124-android-13-124-realme-5-series-r5x.webp "Welcome back, tech enthusiasts! In this video, we're diving deep into the Afterlife Project 5.0, the latest and greatest custom ROM tailored specifically for Realme 5, 5i, and 5s devices.<br/><br/> What's New in Afterlife Project 5.0:<br/><br/>Experience unparalleled performance enhancements designed to turbocharge your Realme device.<br/>Unleash a whole new level of customization with a plethora of exciting features and tweaks.<br/>Enjoy a smoother, more responsive user interface that takes your smartphone experience to the next level.<br/>Say goodbye to bloatware and hello to a cleaner, leaner system for optimal efficiency.<br/>Explore enhanced battery optimization techniques to squeeze every last drop of juice from your device. <br/>---------------------------------------------------------------------------------------------------------------------------<br/>Download link :- pending (on telegram)<br/>telegram:- https://t.me/r5x_special")
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