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Episode 3 of BrainStorm Live - Amprion’s CEO Dr. Russ Lebovitz talks about the earliest molecular changes associated with Alzheimer's and Parkinson's. These changes involve the formation of small soluble aggregates of misfolded proteins within the brain. Known as Prions, these soluble aggregates can replicate slowly within the brain by causing other normal proteins to misfold, forming new Prions. They can also move from cell to cell. These Prions have long incubation period, and are highly des
⏲ 1 min 11 sec ✓ 26-Jan-2018
Episode 7 of BrainStorm Live - Amprion's CEO Dr. Russ Lebovitz discusses the molecular basis of Synuclein, a type of Prion (aka misfolded-protein) underlying Parkinson's disease and compares this with the molecular footprint and Prion structures associated with Alzheimer's.nn============nJoin us and be the first to know as soon as Amprion’s breakthrough Prion Early Detection Testing℠ for Alzheimer’s & Parkinson’s becomes available.nnFollow @AmprionMe to join the fight to end Alzheime
⏲ 1 min 75 sec ✓ 26-Jan-2018
Episode 20 of BrainStorm Live - Amprion's CEO Dr. Russ Lebovitz discusses the impact Alzheimer's has on women vs. men.Recent studies suggest that Women may show symptoms of dementia at earlier stages of the disease compared with men. Early diagnosis, may therefore be even more important for women than for men.nn============nJoin us and be the first to know as soon as Amprion’s breakthrough Prion Early Detection Testing℠ for Alzheimer’s & Parkinson’s becomes available.nnFollow @Ampr
⏲ 1 min 70 sec ✓ 19-Sep-2018
Episode 23 of BrainStorm Live - Amprion's CEO Dr. Russ Lebovitz talks about the importance of accurate early diagnosis despite the lack of effective treatment, as early detection has been the missing key in finding the cure. Effective treatment may need to start before any symptoms have appeared. Early biomarkers are therefore essential for optimal treatment.nJoin us and be the first to know as soon as Amprion’s breakthrough Prion Early Detection Testing℠ for Alzheimer’s & Parkinson’
⏲ 1 min 44 sec ✓ 19-Sep-2018
Episode 22 of BrainStorm Live - Amprion's CEO Dr. Russ Lebovitz explains the role genetics play in Alzheimer's.Genetic markers have been identified that increase the probability of early onset of Alzheimer's. Many of these markers appear to be involved in the processing and clearance of misfolded proteins and prions in the brain. The most important of these appears to be ApoE4, which may both accelerate misfolding as well as enhance the damage caused by the misfolded proteins.nn============nJo
⏲ 2 min 17 sec ✓ 19-Sep-2018
Phosphatidylserine (DHM) (51446-62-9) Manufacturers - Phcokernnhttps://www.phcoker.com/product/51446-62-9/nnPhosphatidylserine SpecificationsnnnnProduct NamenPhosphatidylserine (DHM)nnnChemical NamenPhosphatidyl-L-serine;1,2-Dioctadecanoyl-sn-glycero-3-phosphoserine;Ptd-L-Ser;PS;nnnBrand NamenN/AnnnDrug ClassnN/AnnnCAS Numbern51446-62-9nnnInChIKeynTZCPCKNHXULUIY-RGULYWFUSA-NnnnMolecular FormulanC42H82NO10PnnnMolecular Weightn792.1 g/molnnnMonoisotopic Massn791.567635 g/molnnnBoiling po
⏲ 33 sec ✓ 21-Mar-2020
Episode 10 of BrainStorm Live - Amprion’s CSO Dr. Claudio Soto talks about the critical need of new technologies in early detection for Alzheimer's, Parkinson's and other neurodegenerative diseases. The absence of accurate early detection is the primary reason for the lack of effective treatments today despite enormous spending in drug development over the past three decades. There is not even a single drug that passes the FDA approval for Alzheimer’s and Parkinson’s today. Amprion’s rev
⏲ 70 sec ✓ 26-Jan-2018
Episode 15 of BrainStorm Live - Amprion's CEO Dr. Russ Lebovitz explains the bad actors that drive the progression of Alzheimer's and Parkinson's—three types of Prions named Abeta, Tau and Synuclein in their soluble aggregate forms. By detecting these elusive rogue proteins early, Amprion’s breakthrough Prion Early Detection Science℠ accelerates the successful development of effective treatments for Alzheimer’s and Parkinson’s. nn============nJoin us and be the first to know as soon as
⏲ 2 min 19 sec ✓ 26-Jan-2018
Episode 24 of BrainStorm Live - Amprion's CEO Dr. Russ Lebovitz talks about the challenges in developing effective treatment for Alzheimer's. Absence of early biomarkers has been the greatest challenge thus far. Amprion's novel detection of misfolded proteins and prions is likely to accelerate successful development of new therapies.nn============nJoin us and be the first to know as soon as Amprion’s breakthrough Prion Early Detection Testing℠ for Alzheimer’s & Parkinson’s becomes av
⏲ 1 min 55 sec ✓ 19-Sep-2018
Prion disease treatment endeavors to combat the devastating neurodegenerative effects of these elusive disorders. Current approaches aim to target the pathological accumulation of misfolded prion proteins in the brain, with immunotherapy emerging as a promising avenue. Immunotherapeutic strategies involve stimulating or enhancing the immune system to recognize and clear abnormal prions, offering potential disease-modifying effects. Challenges such as blood-brain barrier penetration, disease hete
⏲ 37 sec ✓ 07-May-2024
Dr. Joel Wallach -Chronic Wasting Disease Daily with Doc and Becca 1/31/24nnDr. Wallach discusses CWD - Chronic Wasting Disease.According to the CDC - CWD is a progressive, fatal disease that affects the brain, spinal cord, and many other tissues of farmed and free-ranging deer, elk, and moose. CWD belongs to a family of diseases called prion diseases or transmissible spongiform encephalopathies (TSEs)nDr. Wallach states that their Hypothesis of cause to be incorrect and discusses why in today
⏲ 45 min 4 sec ✓ 01-Feb-2024
New Podcasting of Bentham Science Publishers https://youtu.be/5PrSq-xBr5Y:nMy name is Jiapu Zhang, a Research Scientist in computing of Optimization and Bioinformatics. This talk is talking about my recent 'Research Article' (Molecular Dynamics Studies of the Buffalo Prion Protein Structured Region at Higher Temperatures) published in The Open Bioinformatics Journal, Volume 13, pages 129-136 (https://benthamopen.com/contents/pdf/TOBIOIJ/TOBIOIJ-13-129.pdf).nnPrion diseases are also called
⏲ 1 min 41 sec ✓ 08-Apr-2021
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